ChromSoc nitrilase flow chemistry project 1

I have an undergraduate student, Rob, working with us this summer on nitrilase reactions. He is kindly sponsored by the Chromatographic Society to work on a project using HPLC and GC to compare batch processes run on immobilized enzyme in a flask with those run on the same enzyme preparation using our in-house mesoscale flow reactor system. The flow reactor system is something we have been working on for a while and its genesis was part of a project based around using 3D printing to make bespoke laboratory equipment which is described in the Tumblr blog here, with a video of the system in operation doing a nitro reduction here. My intention is to relate here a real time log of progress with this project.

Two copies of the track fit together, and the solution

is flowed through. The track contains enzyme immobilized

on beads.